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"Volatile" also means that gyromitrin has a low boiling point, and thus mushrooms containing it can have a puzzling non-effect on some, whereas others are severely poisoned. In Europe, it has sometimes only been the cooks who have died from Gyromitra esculenta. The dividing line between a "safe and "lethal dose" is very slim. Numerous studies have been carried out (most notably by David Nutt and Imperial College, London) into the usefulness of psilocybin mushrooms, particularly in the treatment of depression. The findings of these studies show a high correlation between controlled psilocybin experiences and the lessening of depression in subjects, sometimes from as little as one psilocybin experience. Onset of symptoms usually occurs within an hour of ingestion, and effects typically last up to four to six hours. Effects are primarily psychological and perceptual, including heightened color perception, emotional effects such as religious ecstasy or anxiety, and sometimes hallucinations or delusions. As with any other psychologically-active substance, mindset and situation can greatly influence psilocybin's subjective effects. https://mushroomgrowingcanada.com/ should be taken not to frighten or upset a person under its influence, and if a victim does become anxious, to reassure them that the effects are temporary. Little research has been done on antitoxins, but tryptophan may have a mitigating effect.